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β-Carboline
β-Carboline
Salts
[]
β-Carboline hydrochloride
β-Carboline hydrochloride
Molecular structure via molpic
Molecular formulaC11H8N2
Molecular mass168.19 g/mol
Predicted LogP3.2
Melting point199 °C
Solubility>25.2 [ug/mL] (The mean of the results at pH 7.4)
Chiralityachiral
Identifiers
[]
IUPAC name9H-pyrido[3,4-b]indole
SMILESC1=CC=C2C(=C1)C3=C(N2)C=NC=C3
InChIInChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H
InChIKeyAIFRHYZBTHREPW-UHFFFAOYSA-N

β-Carboline

β-Carboline (also known as 9H-Pyrido[3,4-B]indole, Norharman, Norharmane, 2,9-Diazafluorene, Carbazoline, 9H-β-carboline, 2-Azacarbazole, 2H-Pyrido[3,4-b]indole, .β.-Carboline or Nor Harmane) is a substance of the beta-carboline class.

Chemistry

β-Carboline is typically found in the form of its hydrochloride salt.

Stereochemistry

β-Carboline is a achiral mixture

Pharmacology

Predicted binding sites (SwissTargetPredictions)[]
TargetTarget ClassProbability
Sodium-dependent Norepinephrine Transporter0.43
Sodium-dependent Serotonin Transporter0.43
Sodium-dependent Dopamine Transporter0.43
Trace amine-associatedReceptor 10.43
Trace amine-associatedReceptor 20.43
Monoamine oxidase Enzyme A0.34
Monoamine oxidase Enzyme B0.34
Sigma non-opioid intracellularReceptor 10.34
SerotoninReceptor 2A0.30
SerotoninReceptor 2C0.30

See also