Bluedark

Desomorphine
Desomorphine
Salts
[]
Desomorphine hydrobromide
Desomorphine hydrobromide
Desomorphine hydrochloride
Desomorphine hydrochloride
Molecular structure via molpic
Molecular formulaC17H21NO2
Molecular mass271.35 g/mol
AppearanceRectangular plates from acetone-water
Predicted LogP2.8
Boiling pointSublimes in high vacuum between 140 and 170 °C
DecompositionWhen heated to decomposition it emits toxic fumes of /oxides of nitrogen/.
SolubilitySoluble in acetone, ethyl acetate
Chiralityabsolute
Identifiers
[]
IUPAC name(4R,4aR,7aS,12bS)-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol
SMILESCN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3CCC4
InChIInChI=1S/C17H21NO2/c1-18-8-7-17-11-3-2-4-14(17)20-16-13(19)6-5-10(15(16)17)9-12(11)18/h5-6,11-12,14,19H,2-4,7-9H2,1H3/t11-,12+,14-,17+/m0/s1
InChIKeyLNNWVNGFPYWNQE-GMIGKAJZSA-N

Desomorphine

Desomorphine (also known as Dihydrodeoxymorphine, Permonid, Desomorfina, Krokodil, Deoxydihydromorphine D, Dihydrodesoxymorphine D, Desomorphinum, Desomorfin, Dihydrodesoxymorphine-D or 4,5-Epoxy-3-hydroxy-N-methylmorphinan) is a opioid substance of the morphinan class.

Chemistry

Desomorphine is typically found in the form of its hydrobromide and hydrochloride salts.

Stereochemistry

Desomorphine is a absolute mixture

Pharmacology

Predicted binding sites (SwissTargetPredictions)[]
TargetTarget ClassProbability
Sodium-dependent Norepinephrine Transporter0.43
Sodium-dependent Serotonin Transporter0.43
Sodium-dependent Dopamine Transporter0.43
Trace amine-associatedReceptor 10.43
Trace amine-associatedReceptor 20.43
Monoamine oxidase Enzyme A0.34
Monoamine oxidase Enzyme B0.34
Sigma non-opioid intracellularReceptor 10.34
SerotoninReceptor 2A0.30
SerotoninReceptor 2C0.30

See also