Bupropion

Bupropion
Bupropion
Molecular structure via molpic
Molecular formulaC13H18ClNO
Molecular mass239.74 g/mol
AppearancePale yellow oil
Melting point233-234 °C
Boiling point52 °C
SolubilityVery hygroscopic and susceptible to decomposition
Chiralityracemic
Identifiers
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IUPAC name2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
Cannonical SMILESCC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C
InChIInChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3
InChIKeySNPPWIUOZRMYNY-UHFFFAOYSA-N
Dosing
Insufflated
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Threshold1 - 26.250000000000007 mg
Light26.250000000000007 - 75 mg
Common75 - 150 mg
Strong150 mg
Heavy150 - 222.49999999999997 mg
Oral
[]
Threshold1 - 82.50000000000001 tablet
Light82.50000000000001 - 150 tablet
Common150 - 300 tablet
Strong300 - 450 tablet
Heavy450 - 600 tablet
Statistically derived dosages by Sernyl

Bupropion (also known as Amfebutamone, Amfebutamon, Wellbutrin, 34841-39-9, amfebutamonum, Amfebutamona, Elontril, (+-)-Bupropion, Wellbatrin or Amfebutamonum [INN-Latin]) is a depressant substance of the methcathinone class.

Chemistry

Bupropion is typically prepared in the form of its amine salts hydrobromide, hydrochloride and maleate.

Bupropion is a racemic mixture of two optical stereoisomers.

See also