Bluedark

Venlafaxine
Venlafaxine
Salts
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Venlafaxine hydrochloride
Venlafaxine hydrochloride
Molecular structure via molpic
Molecular formulaC17H27NO2
Molecular mass277.4 g/mol
Predicted LogP2.9
Melting pointCrystals from ethyl acetate; melting point 102-104 °C; specific optical rotation: +27.6 deg (c = 1.07 in 95% ethanol) /Venlafaxine (+)form/
SolubilityMolecular weight: 313.86. White to off-white crystalline solid from methanol/ethyl acetate, mp 215-217 °C. SOlubility (mg/mL): 572 water. Partition coefficient (octanol/water): 0.43 /Venlafaxine hydrochloride/
Chiralityracemic
Identifiers
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IUPAC name1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol
SMILESCN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O
InChIInChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3
InChIKeyPNVNVHUZROJLTJ-UHFFFAOYSA-N
Dosing
Oral
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Threshold20 - 37.5 mg
Light37.5 - 56.25 mg
Common56.25 - 75 mg
Strong75 - 131.25 mg
Heavy131.25 - 150 mg
Statistically derived dosages by Sernyl

Venlafaxine

(Redirected from (-)-Venlafaxine)

Venlafaxine (also known as D,L-Venlafaxine, Venlafaxina, Elafax, Venlafaxinum, Efectin, velafax, 1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol, Venlafexine, Kanghong or Trevilor) is a antidepressant substance of the phenethylamine class.

Chemistry

Venlafaxine is typically found in the form of its hydrochloride salt.

Stereochemistry

(RS)-Venlafaxine is a racemic mixture of the optical stereoisomers:
Stereoisomers
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(+)-Venlafaxine(-)-Venlafaxine
(+)-Venlafaxine (-)-Venlafaxine

See also