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Promethazine
Promethazine
Salts
[]
Promethazine maleate
Promethazine maleate
Promethazine hydrochloride
Promethazine hydrochloride
Promethazine salicylate
Promethazine salicylate
Molecular structure via molpic
Molecular formulaC17H20N2S
Molecular mass284.4 g/mol
AppearanceCrystals
Predicted LogP4.8
Melting point140 °
Boiling point374 to 379 °F at 3 mmHg (NTP, 1992)
DecompositionWhen heated to decomposition it emits very toxic fumes of /nitrogen oxides and sulfur oxides/.
SolubilityVery soluble in dilute hydrogen chloride
Chiralityracemic
Identifiers
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IUPAC nameN,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
SMILESCC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C
InChIInChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
InChIKeyPWWVAXIEGOYWEE-UHFFFAOYSA-N
Dosing
Oral
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Threshold1 - 15 mg
Light15 - 25 mg
Common25 - 50 mg
Strong50 - 100 mg
Heavy100 - 112 mg
Statistically derived dosages by Sernyl

Promethazine

Promethazine (also known as Proazamine, Diphergan, Protazine, Promethazin, Prometazin, Vallergine, Dimapp, Fargan, Procit or Promazinamide)

Chemistry

Promethazine is typically found in the form of its maleate, hydrochloride and salicylate salts.

Stereochemistry

Promethazine is a racemic mixture of the optical stereoisomers.

See also