Bluedark

Naloxone
Naloxone
Salts
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Naloxone hydrochloride
Naloxone hydrochloride
Naloxone hydrochloride dihydrate
Naloxone hydrochloride dihydrate
Molecular structure via molpic
Molecular formulaC19H21NO4
Molecular mass327.4 g/mol
AppearanceCrystals from ethyl acetate
Predicted LogP2.1
Melting point178 °C
DecompositionWhen heated to decomposition it emits toxic fumes of /nitrogen oxides/.
SolubilitySoluble
Chiralityabsolute
Identifiers
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IUPAC name(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
SMILESC=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O
InChIInChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
InChIKeyUZHSEJADLWPNLE-GRGSLBFTSA-N
Dosing
Sublingual
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Threshold0.125 - 0.25 mg
Light0.25 - 1 mg
Common1 - 1.5 mg
Strong1.5 - 2 mg
Heavy2 - 3 mg
Statistically derived dosages by Sernyl

Naloxone

Naloxone (also known as l-Naloxone, n-Allylnoroxymorphone, (-)-Naloxone, Narcan, Naloxona, EN 1530 base, Naloxonum, Nalossone, N-Allyl-noroxymorphone or DBL Naloxone) is a opioid substance of the morphinan class.

Chemistry

Naloxone is typically found in the form of its hydrochloride and hydrochloride dihydrate salts.

Stereochemistry

Naloxone is a absolute mixture

See also