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Methadone
Methadone
Salts
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Methadone hydrobromide
Methadone hydrobromide
Methadone hydrochloride
Methadone hydrochloride
Methadone hydriodide
Methadone hydriodide
Molecular structure via molpic
Molecular formulaC21H27NO
Molecular mass309.4 g/mol
Predicted LogP3.9
Melting point99.5 °C
DecompositionWhen heated to decomposition it emits toxic fumes of /nitrogen oxides/.
SolubilityPlatelets from alcohol + ether; mp, 235 °C; bitter taste; UV maximum, 292 nm; solubility (g/100 mL) water, 12; alcohol, 8; isopropanol, 2.4; Practically insoluble in ether, glycerol; pH of a 1% aqueous solution is 4.5-5.6 /Methadone hydrochloride/
Chiralityracemic
Identifiers
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IUPAC name6-(dimethylamino)-4,4-diphenylheptan-3-one
SMILESCCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
InChIInChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3
InChIKeyUSSIQXCVUWKGNF-UHFFFAOYSA-N
Dosing
Oral
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Threshold0.5 - 1 mg
Light1 - 5 mg
Common5 - 10 mg
Strong10 - 20 mg
Heavy20 - 29.10000000000001 mg
Statistically derived dosages by Sernyl

Methadone

Methadone (also known as Diaminon, Dolophin, Phenadone, Heptadone, Amidone, Ketalgin, Methadon, Adanon, Physeptone or Algovetin)

Chemistry

Methadone is typically found in the form of its hydrobromide, hydrochloride and hydriodide salts.

Stereochemistry

Methadone is a racemic mixture of the optical stereoisomers.

See also