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Hydrocortisone
Hydrocortisone
Esters
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Hydrocortisone acetate
Hydrocortisone acetate
Hydrocortisone valerate
Hydrocortisone valerate
Hydrocortisone cypionate
Hydrocortisone cypionate
Molecular structure via molpic
Molecular formulaC21H30O5
Molecular mass362.5 g/mol
AppearancePlates from alc or iso-propyl alc
OdorOdorless
TasteBitter taste
Predicted LogP1.6
Melting point217-220 °C with some decomposition
SolubilityAmorphous, hygroscopic, white powder. Mp 169.0-171.2 °C. Solubility in water: approx 500 mg/mL. Similarly soluble in methanol, ethanol,; sparingly soluble in chloroform. /21-Sodium succinate/
Chiralityabsolute
Identifiers
[]
IUPAC name(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
SMILESC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O
InChIInChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChIKeyJYGXADMDTFJGBT-VWUMJDOOSA-N

Hydrocortisone

Hydrocortisone (also known as Cortisol, Acticort, Cetacort, Cortef, Hydrasson, Hydrocortisyl, Hydrocortone, Cobadex, Hytone or Cortenema) is a substance of the steroid class.

Chemistry

Hydrocortisone is typically found in the form of its acetate, valerate and cypionate esters.

Stereochemistry

Hydrocortisone is a absolute mixture

See also