Lorazepam

Lorazepam
Lorazepam
Molecular structure via molpic
Molecular formulaC15H10Cl2N2O2
Molecular mass321.2 g/mol
Melting point192-194
Solubility1.76e-02 g/L
Chiralityracemic
Identifiers
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IUPAC name7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
Cannonical SMILESC1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl
InChIInChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
InChIKeyDIWRORZWFLOCLC-UHFFFAOYSA-N
Dosing
Oral
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Threshold0.3 - 0.5 mg
Light0.5 - 1 mg
Common1 - 2 mg
Strong2 - 3 mg
Heavy3 - 4 mg
Statistically derived dosages by Sernyl

Lorazepam (also known as Ativan, o-Chloroxazepam, o-Chlorooxazepam, Temesta, Loraz, Bonatranquan, Anxiedin, Lorabenz, Sedatival or Orfidal) is a depressant substance of the amine class.

Chemistry

Lorazepam is a racemic mixture of two optical stereoisomers.

See also